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Laufs U, Liao JK

DARU J Pharm Sci 34 , 34 (2026)

These findings were supported by electrophysiological assays using Ussing chambers that demonstrated viniferins potent ability to inhibit ATP-stimulated Cl secretion across the colonic epithelium, suggesting a pharmacologically relevant suppression of CaCC-mediated ion transport

Modified treatment strategies (mentioned above) should be considered at this point to improve symptoms and allow for reduced doses of L-dopa

Although CTPS2 does not show a significant correlation with advanced disease stage and poor prognosis in these cancer types, CTPS2 expression levels have been linked to fluorouracil-resistant colorectal cancer (Tan et al., 2011)