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Since the sensitivity and specificity of these approaches arent satisfying, related biomarkers for diagnosis could be considered such as carbohydrate antigen 19 9 (CA 19 9), macrophage inhibitory cytokine 1 (MIC-1), and the immunoglobulin carcinoembryonic antigen-related cell adhesion protein 1 (CEACAM1) [4, 6]

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10.1021/ja411006a 198 SpatolaM.WiderC

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In addition, as reflected by decreased levels of vascular cell adhesion molecule 1 (VCAM-1), it also reduced VEGF-A-induced endothelial activation ( It is recently reported that because the VEGFR2 was blocked by using a VEGFR2 kinase inhibitor SU5416 in experimental diabetic mode, these mice models developed histological characteristics mimicking the key features of advanced human DN