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This suggests that during advanced, late stages of AD, the pathology is irreversible and therefore the opportunity to prevent or delay AD is during the earliest preclinical stages when the initial, disease aggravating oxidative stress occurs

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We may also ask about any allergies or previous reactions to IV treatments

Abbreviations AFP: Alpha-fetoprotein ALT: Alanine transaminase Apo B: Apolipoproteins B Apo-A1: Apolipoproteins A-1 AST: Aspartate aminotransferase A-T: Ataxia-telangiectasia ATM: Ataxia-telangiectasia mutated BMI: Body mass index CVDs: Cardiovascular diseases FAPESP: So Paulo Research Foundation GGT: Gamma-glutamyl transpeptidase GPx: Glutathione peroxidase activity H/A: Height for age HD: Heart disease HDL-c: High-density lipoprotein cholesterol HOMA-IR: Homeostasis Model Assessment of Insulin Resistance IEI: Inborn errors of immunity IQ: Interqartile interval IVIG: Intravenous immunoglobulin LDL-c: Low-density lipoprotein cholesterol LDLox: Oxidized LDL MDA: Malondialdehyde MUAC: Mid-upper arm circumference NCEP: National Cholesterol Education Program NFkB: Nuclear transcription factor NHDL-c: Non-HDL-c ROS: Reactive oxygen species Se: Selenium TC: Total cholesterol TG: Triglycerides us-CRP: Ultra-sensitive C-reactive protein VLDL-c: Very-low-density lipoprotein cholesterol References Cardoso BR, Ganio K, Roberts BR

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