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Roughly expressed, the qualifier agent-based means the dynamics of the computationally implemented system are driven by interactions among software entities called agents with encapsulated states (data, attributes, and/or methods), starting from initial user-specified conditions
doi: 10.1111/nyas.12822

However, additional randomized clinical studies are needed to define its effectiveness in this setting

Firstly, although we observed that the frequency and magnitude of Ca 2+ oscillation were more pronounced in cells from GCGR-KO mice, the detailed mechanism still needs to be elucidated
Given that the majority of these studies were conducted in Western populations, further research in diverse ethnic groups is warranted