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There is no FDA-approved drug that directly eliminates or reverses tinnitus [6-10]

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Notably, RT-qPCR analysis showed a sharp increase in OCT4 mRNA expression, a marker of pluripotent stem cells and essential for TIC self-renewal [33], in the colonies formed in 3D gels relative to 2D culture conditions (Fig

The term syndrome suggests that the underlying cause of MetS is not readily identifiable, and it was not initially expected that a singular, comprehensive pathological etiology would exist for MetS (16)