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In vivo experiments in mice with lung adenocarcinoma and mitogen-activated protein (MEK) and cyclin-dependent kinase 4/6 (CDK4/6) inhibition-induced senescence, the urokinase-type plasminogen activator receptor (uPAR)-directed CAR-T cells effectively depleted senescent tumor cells and prolonged survival

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It has been shown in animal studies to be important in wound healing and inflammatory responses

During these stages, the structure of the endometrium undergoes some changes
