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2016;11:e0159414

Continued investigations into synergistic regimens, targeted drug delivery, and clinical safety profiles are of utmost importance for fully realizing artemisinins therapeutic potential in cancer treatments

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Uncontrolled hypertension or active cardiovascular event

No additive function of Bdnf- and Igf-1-mediated survival is reported from different cellular sources [102,116], however other data is contradictory in finding additive affects on prenatal rat hippocampal cell survival [117] that cumulate on increased pGsk-3