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doi: 10.1016/j.jhep.2021.06.028 94 LiJLiJPengYDuYYangZQiX
Limiting excitoxicity using NMDA receptor antagonists protects against neurodegeneration in multiple neurologic disorders, including human and mouse models of Alzheimers disease and ischemic stroke (3, 9, 10)
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In the apo- Lb TDC structure, the imidazole ring of H241 is anchored by two water molecules and is distant from the PLP binding pocket, and the side chain of K240 is placed in a position near the PLP binding pocket
