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Heavy residue, sweat, styling creams, and oil buildup can make curls feel dull, uneven, or harder to manage over time, but overly harsh shampoos can also leave curls rough, frizzy, and difficult to style afterward

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FIGURE 8 3.3 Urinary system diseases Plasma levels of TMAO have been found to have a clear association with various human urinary system diseases and serve as a key biomarker for several kidney diseases ( 3.3.1 Chronic kidney disease (CKD) Metabolomic analysis shows that chronic kidney disease (CKD) patients have higher plasma TMAO concentrations (Prokopienko et al., 2019)

A study involving hypothyroid patients showed that borderline-to-low B12 levels were more frequent in both overt and subclinical hypothyroidism groups compared with controls [95]