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Dave R, Randhawa G, Kim D, Simpson M, Hoare T

Furthermore, the induction of FSP1 condensate formation within tumor cells triggers the phase separation of FSP1, ultimately inducing ferroptosis in cancer cells
doi: 10.1152/physrev.00023.2017 138 DavieJR

Samples were briefly centrifuged at 2000g for 2 minutes to pellet hemibrain, then supernatant was carefully removed

It binds to KRAS G12C mutants and locks KRAS in an inactive state, thereby irreversibly inhibiting KRAS activity
