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[10] Conversely, starting or stopping thyroid hormone replacement could alter the growth hormone response

Without enough B12, MMA and homocysteine back up and accumulate

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Unlike vitamins A, D, E, and K which are stored in fat, B vitamins are water soluble and not stored in large quantities

For example, animals like sheep and cows produce B12 internally due to their intestinal bacteria (not present in humans), which goes into their milk