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Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors

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This system is responsible for regulating: Heart rate Blood pressure Digestion Temperature regulation A host of other involuntary functions Autonomic nervous system dysfunction manifests most commonly as POTS (postural orthostatic tachycardia syndrome), a condition in which heart rate spikes abnormally upon standing, causing dizziness, palpitations, and near-syncope

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Down-regulation of cholesterol 7-hydroxylase ( CYP7A1 ) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway