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PMO irreversibly inhibits acetylcholinesterase (AChE), encoded by the Ace1 gene, an enzyme essential for neurotransmission 9,10,11

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S.KimD.HwangG

10.1002/ptr.8168 73 WangF

Loss of CDK4 expression causes insulin-deficient diabetes and CDK4 activation results in beta-islet cell hyperplasia