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Administering hepsin to wild-type mice increases APAP tolerance and downregulates GJ expression Considering the potential clinical and medical applications, we evaluated a therapeutic strategy involving the administration of hepsin to wild-type adult mice and assessed its potential to mitigate APAP-induced liver injury

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In addition to its healing properties with heart tissue, it appears proangiogenic, works to reduce infarct volume, preserves cardiac function in preclinical models, and is antifibrotic