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Our group [262] developed a multilayered defensive platform (IL-4@PEGRA NAs) with a size of 96.45 7.3 nm via the self-assembly of polycatechol-containing poly(ethylene glycol)-ylated phenolic rosmarinic acid (PEGRA) and IL-4, to preserve bioactivity and prolong circulation time

It is notable that in influenza, shorter time between the onset of symptoms and the start of antiviral treatment results in improved outcomes such that the CDC primarily recommends starting treatments within 48-h 68

48 Johnson JE and Wright LF

[DOI] [PMC free article] [PubMed] [Google Scholar] [62].Lo HW, Ali-Osman F

Regulation of the germinal center response by microRNA-155
