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High doses can cause liver damage or worsen certain medical conditions

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Disease eradication using PZQ monotherapy is severely limited by the low activity of this drug against juvenile worms

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(2024), it was observed that oral administration of the probiotic Lactobacillus reuteri exhibited significant enhancement in intestinal barrier function impairment associated with AKI, while also regulating the composition of intestinal microbiota and its related metabolites