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Description
The gene cluster encoding this pathway contains an enzyme homologous to GS enzymes (IpuC), a cytochrome P-450 monooxygenase (IpuD), and a GAT family protein (IpuF)
From Traditional Drug Design to Catalytic Metallodrugs: A Brief History of the Use of Metals in Medicine
doi: 10.1007/s11060-009-0011-5
In a phase I study of advanced resistant solid tumors, GMX-1778 (CHS-828) induced gastrointestinal toxicity and thrombocytopenia
Additionally, cannabidivarin (CBDV) has been found to modulate the glutamate-GABA system in the basal ganglia without affecting the corresponding system in the frontal regions (165167)
