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In vivo neuroprotective activity has been evaluated in different models of neurotoxicity: corticosterone (Yu et al., 2020a

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Immunol 9(12):82332 [DOI] [PubMed] [Google Scholar] 43.Rathmell JC, Vander Heiden MG, Harris MH, Frauwirth KA, Thompson CB

Finally, most studies are preclinical, based on cell and animal models, and lack valid clinical evidence