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Chapter 22The effects of catechins on the cardiac mitochondria

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73 In mice, systemic cNADK knockout led to either embryonic or preweaning lethality

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This effect is blocked by glutamatergic antagonist CNQX [cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione)] and AP5 (2-amino-5-phosphopentanoic acid), suggesting that interneuron-astrocyte-mediated potentiated inhibition of pyramidal neurons depends on astrocyte-mediated glutamate release (Kang et al., 1998)

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