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Cecchelli R, Aday S, Sevin E, Almeida C, Culot M, Dehouck L, et al

PMID: 10223088 Our findings suggest that acetaminophen administration selectively depletes (within 2 hr) mitochondrial glutathione, and produces local toxicity by altering membrane permeability and decreasing the efficiency of oxidative phosphorylation

Participants on the 5mg dose lost an average of 16.0% of their body weight

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