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The remaining patients have a more severe form of the disease that is usually caused by the inheritance of two different defects (a state known as compound heterozygosity)
[DOI] [PubMed] [Google Scholar] 157.Jurkowska H., Wrbel M., Jasek-Gajda E., Rydz L
6 ChenJ
Nature 575, 688692
Long-term treatment with oral antibiotics can also lead to biotin deficiency
