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The Wnt pathway controls the expression of genes required by stem cells to proliferate in the crypt floor region, which is the basic process for maintaining mucosal homeostasis
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Comparison of the mechanisms of action reveals similar pathways for these metals to induce toxicity including ROS generation, weakening of the antioxidant defense, enzyme inactivation, and oxidative stress
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway
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