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High-dose use While trials have tested up to 1200mg/day (even as high as 2400mg/day) and illustrated safety, some report higher rates of gastrointestinal side effects, dizziness, and skin reactions at these levels.14 28 38 Additionally, these higher doses are often short-term (35 weeks) and used under clinical supervision

Bocci, V

Nutrients 14(24):5308

Enhances Skin Texture: Leaves skin smoother, softer, and more resilient

Within this context, these early signals should be regarded as exploratory rather than definitive, and their potential benefits require confirmation through larger, rigorously designed randomized controlled trials