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The role of the perinatal period (immediately before and after birth) is also of interestcould interventions in the neonatal period (like supplementing newborns in the nursery, or enhancing maternal nutrition during breastfeeding) influence outcomes for high-risk siblings of children with ASD

[DOI] [PubMed] [Google Scholar] Urata Y, Yamamoto H, Goto S, Tsushima H, Akazawa S, Yamashita S, Nagataki S, Kondo T

A 2020 preclinical study evaluating gabapentin in an experimental colitis model demonstrated: Reduced visceral hypersensitivity Decreased inflammatory signaling Reduced mast cell density and activation markers in colonic tissue Downregulation of pro-inflammatory pathways (including NF-B signaling) Mast cells and enteric nerves communicate bidirectionally in the gut

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