glutathione and the methylation cycle Overview of Methionine Folate Metabolism Methylation is one of the
Description
Hence, the low levels of thiomethyl metabolites observed after APAP exposure are probably associated to the limited cytochrome P450 capabilities of in vitro models to generate NAPQI metabolites via CYP2E compared to in vivo hepatocytes
PMC 3785061

Figures above are estimates drawn from Aetna Colorado patterns and our clinics recent experience

doi: 10.1016/j.chemosphere.2015.08.031

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