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In hMDMs, specifically blocking DAT activity enhanced LPS-mediated production of IL-6, TNF- , and mitochondrial superoxide levels, showing that the regulation of dopamine uptake and release, as well as dopamine receptor activity, plays a role in dopaminergic immunomodulation in macrophages (Mackie et al., 2022)
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In addition, ferroptosis may upregulate subcellular structures such as hazardous peroxisomes on the surface of fractured organelles or ruptured mitochondria
(2020) 83:e13202
The toxicology of mercury and its chemical compounds
