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446,448 Although fMLP also activated PI3K to a lesser extent than CXCL8-induced expression, the concomitant addition of chemokines and fMLP resulted in the inhibition of PI3K activity, indicating that the p38 MAPK pathway may inhibit the PI3K pathway (Fig

Kind of the same region

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As a consequence, CpG 5 islands flanking the repeats as well as the repeats itself, which also function as a CpG island, become hypermethylated and render the gene inactive (Hansen et al., 1992)

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