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For skin whitening, reduced glutathione works by inhibiting melanin production, which is responsible for skin pigmentation
Thioredoxin (Trx), present in the cytosol as Trx1 and in mitochondria as Trx2, is oxidized and upregulated in response to oxidative stress and elevated ROS levels
However, no significant effects were observed on IOP, visual acuity, central corneal thickness (CCT), ganglion cell complex (GCC) on optical coherence tomography (OCT), or quality of life measures (NCT04088084)
Niacin Active is a supplement containing nicotinamide
doi: 10.5811/westjem.2020.1.45944
