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On the other hand, pyridoxine is the coenzyme of dopa decarboxylase, converting L-DOPA to dopamine 49 , which raises a concern that pyridoxine supplementation may result in peripheral metabolism of L-DOPA and a lack of bioavailability in the brain 58

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65 HimotoT.FujitaK.NomuraT.TaniJ.MiyoshiH.MorishitaA.et al (2016)