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We also observed a significant preservation of corpus callosum width (axonal myelination), a significant decrease in degenerating neurons, a reduction in Iba1 (microglial marker), decreased lipid peroxidation, and preservation of brainderived neurotrophic factor (BDNF) in the brains of Immunocal-pretreated mice compared to untreated TBI mice

An FDA decision is anticipated by late 2026

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Thus, while both peptides and steroids can have beneficial effects, their mechanisms of action and overall effects are markedly different