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Boudokhane 1 , L
Elabela treatment reduced ferroptosis and improved myocardial hypertrophy and remodeling in hypertensive mice by normalizing the levels of xCT and GPX4 [96]
doi: 10.3168/jds.2012-6317 78
The TrxRs differ from GR by having a catalytic selenocysteine redox-active site at the C-terminus in addition to the standard CXXC domain (Lu and Holmgren, 2014)
The exact mechanism of eNOS modification is unknown but in vivo experiments have shown that eNOS activation in aortas and iNOS transgenetic expression in mouse heart both result in NO-induced protein S-glutathionylation
