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H2S has also been demonstrated to promote angiogenesis after hypoxia via up regulation of angiopoietin-1 and 2, VEGF and p-AKT, which may further improve recovery (121)
Cortez, E., Roswall, P
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Notably, elevated levels of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE], a subclass of eicosanoids, activate the intracellular cation channel transient receptor potential vanilloid one and mediate endothelial dysfunction in DM (Otto et al., 2020)
doi: 10.1111/j.1365-2885.2004.00576.x
