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Lai TS, Davies C, Greenberg CS (2010) Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation

It is known that fructose can be further metabolized to produce 3deoxyglucose and fructose3phosphate, both of which are very potent nonenzymatic glycation agents.76 On the other hand, as fructose metabolism by fructokinase, with the consumption of ATP, can bypass the regulation of the glycolytic pathway,77, 78 acetylCoA could be overproduced78 and ATP could be depleted.79 AcetylCoA overproduction could cause nonalcoholic fatty liver disease (NAFLD), as acetylCoA is the precursor of fatty acid,77, 80, 81, 82 while ATP depletion could cause cell death

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Katre P, Bhat D, Lubree H, Otiv S, Joshi S, Joglekar C, Rush E, Yajnik C, et al