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Description
Srivastava et al., 2017)
post-dose, P c = p-value for change from baseline to end of study at pre-dose, P e = p-value end of study at pre-dose comparing placebo vs
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In certain embodiments, the immunomodulating polynucleotide provided herein exhibits stability (e.g., stability against nucleases) that is superior to that of a CpG ODN containing mostly internucleoside phosphate (e.g., more than 50% of internucleoside phosphates) without substantially sacrificing its immunostimulating activity
The changed membrane properties of PKD patients RBCs lead to hemolytic anemia and increase their susceptibility to early splenic destruction [76]
