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It indicates that the patient has type 2 diabetes with suboptimal glycemic control, which provides strong medical necessity for adding or adjusting medication

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Femmes enceintes et allaitantes : bien que les besoins soient accrus, environ 4,5 5 g par jour , la supplmentation doit rester dans les limites nutritionnelles recommandes pour viter tout dsquilibre mtabolique chez le ftus ou le nourrisson

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Heart rate is also phenotype-coupled: near zero at 1 mg in the obese trial cohort, but +10 bpm or more at the same 1 mg in a leaner body from Phase 1b