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Description
Enteric glial cells, crucial for GI function, undergo gliosis in obesity, worsening motility and gut-brain axis dysfunction
Studies suggest its fat-metabolism effects are not directly mediated via 3-adrenergic receptors, though it may increase 3-receptor expression, potentially improving lipolytic sensitivity over time
Large calcifications were also strongly associated with coronary heart disease (OR 4.07, 95% CI 1.1514.44) and atrial fibrillation (p = 0.025)
Source: meta-analyses across SURPASS
In healthy rats, GHRP-2 increased ACTH levels significantly and corticosterone levels modestly
