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Skoulidis F, Li BT, Dy GK, Price TJ, Falchook GS, Wolf J, et al
aeruginosa mutant strain deficient in both gshA and gshB showed a 4-fold and 8-fold increase in sensitivity to hydrogen peroxide and superoxide, respectively, suggesting antioxidant defense of GSH on antibiotics
The two LSU rRNA fragments that define this region correspond to the A-site and P-site segments of the extant PTC (250, 251)
This persistent immune suppression not only dampens T-cell activity but also diminishes the overall effectiveness of ICIs
doi: 10.1210/jc.2016-3591
