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Osteoarthritis and joint pain
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation

Once they reached their target dose, they stayed on that dose as their maintenance dose

Moreover, B12 can help alleviate anxiety by fighting mood swings, loss of focus, and depression

Even when the serum cobalamin concentration is extremely low or undetectable, the homocysteine level will fail to diagnose cobalamin deficiency probably because methionine is commonly added to commercial diets for cats, since it is generally the most limited amino acid in their diet [29]