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However, the finding that mutation of a single aminoacid residue can drastically alter the substrate specificity and other characteristics (Norrgrd et al., 2006) makes these criteria less conclusive for GST class assignments

A generative AI framework was then employed to link and optimize fragments into complete molecules, leading to the identification of four lead compounds with favorable selectivity and drug-like properties after rigorous filtering

403.93 g/mol (Cu complex) Sequence: glycyl-L-histidyl-L-lysine bound to a Cu2+ ion (Gly-His-Lys:Cu) Synonyms: Selected Published Studies The following peer-reviewed studies were conducted using animal models or in vitro cell-culture systems

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