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TFEB enhances PPAR expression during nutrient stress, whereas PPAR activation (such as fenofibrate) induces TFEB expression and nuclear translocation, amplifying lysosomal gene expression and calcium-mediated clearance of hepatic lipid droplets

Patients with major depressive disorder showed decreased amplitudes and delayed/advanced phases of the circadian rhythms such as core body temperature and melatonin [58,59,60]

Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

If serum levels of HoloTC fall into the range of 3549 pmol/L, MMA values above 271 nmol/L suggest B 12 deficiency, and if they are below 271 nmol/L B 12 , deficiency is unlikely

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