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Digests were then labeled by TMT 16-plex reagent following the SL-TMT protocol (64)

SIRT3, as a deacetylase in mitochondria, modulates the transcription of mitochondrial in response to oxidative stress

Finally, 100 l of luciferin detection reagent was added, the plate was briefly shaken and incubated for 15 min and the luminescence was measured

Relugolix combination therapy maintained symptom relief over 52 weeks, with most patients showing no clinically significant decline in bone mineral density [163]