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When SIRT3 removes acetyl groups from isocitrate dehydrogenase 2 (IDH2), more NADPH gets made in mitochondria

De ce fait, en cas dinflammations, il est fortement sollicit et son taux dans lorganisme va baisser

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Rosmarinic acid suppressed cisplatin-induced apoptosis by repressing ROS generation, cytochrome C release, caspase activation, AIF translocation, NF-B activation, IL-1 production, Bax upregulation, and Bcl-2 down-regulation, (Jeong et al

10.1159/000156471 Neuroimmunomodulation 10 BarneaA.RobertsJ