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The weight of the thymus and total thymic cell number did not differ significantly between wild-type and C15orf48 / mice (Supplementary Fig

doi: 10.1016/j.drugpo.2014.10.004 21 StriegelHSimonPFrischSRoeckerKDietzKDickhuthHHet al

For the bottom-up proteomics approach, labeled proteins are enzymatically digested into peptides (typically using trypsin) to generate a complex mixture of peptides, which is then analyzed directly by MS analysis or fractionated using HPLC to reduce the complexity of peptide mixture before MS analysis of each fraction

SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle

Oncogene 40 , 41374150 (2021)