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Pregnant or Breastfeeding Women: Expectant mothers may need additional B12 to support their own health and the development of their baby

Peripheral neuropathy may progress to affect the sensation and function of nerves in the hands, arms, abdomen, and face
those on multiple medications affecting liver function

Their official guidelines for daily intake are as follows: Age 1418: 1.3 mg for males
These research applications continue in laboratory settings to characterize mechanisms and optimize experimental protocols for NAD+-based investigations
