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Moreover, in facing various pathological challenges, the mammalian heart, which possesses high levels of mitochondria and weak antioxidant capacity, is susceptible to oxidant production and oxidative damage

Enhancing GSH synthesis SLC7A11 is an essential molecule that limits the Cys transport rate, thus restricting the synthesis of GSH

doi:10.3945/jn.110.136739 [PubMed][CrossRef] 162

Within the context of the TCA cycle the acetyl-CoA generated by the PDHc is completely oxidized to CO 2 and H 2 O

2003 doi: 10.1016/S0140-6736(03)13413-7
