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Strides towards the development of multi-valent mRNA vaccines are being made each day, for example, a study by Awasthi and colleagues in mice and guinea pigs evaluated a trivalent mRNA LNP vaccine consisting of three different mRNAs encoding for HSV 2 surface glycoproteins shown to each elicit the same level of circulating antibodies when administered in combination as alone demonstrating increased breadth of protection from the combination of effects from each mRNA particle 19

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Cycle Length: Research protocols vary, but use is generally suggested for 3-5 days weekly or continuously for 4-8 weeks to achieve normalization of sleep architecture