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Prolotherapy: Injection of dextrose or other irritant solutions triggering inflammation and healing response

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For example, somewhat optimistic results were described in a subset of pivotal trials (Phase 2 and 3 trials in support of drug/biologic approval) studied by Eshera et al

Yet, our knowledge of the functional properties of neurons that are born after injury within and outside the canonical neurogenic niches and their potential impact on circuit reorganization and on behavioral recovery is still building up

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