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Third, regarding the in vitro assessment of hepatocyte injury, this study primarily relied on LDH release, apoptosis, and cell cycle arrest

Sources: Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P

When monoglutamate folates are taken up into cells, particularly in the liver and kidney where they can be stored (but also in other cells), they are polyglutamated through the action of the enzyme folylpolyglutamate synthase

(2016) described that, besides activating GABA B receptors in astrocytes, GABA release by interneurons also activates GABA A receptors in presynaptic neurons, which inhibited synaptic activity

Additionally, ITCs may enhance antitumor immunity: in experimental models, they promote the activity and proliferation of immune effector cells such as natural killer and T cells, contributing to immunosurveillance against tumors (113)