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doi: 10.1073/pnas.0510565103 27 RavegniniGCargninSSammariniGZanottiFBermejoJLHreliaPet al

Slow, steady pressure over 5 to 10 seconds is ideal

Some people find this feels "weaker" initially because the peak concentration is lower, even though the total weekly drug exposure is similar

The overlapping mechanisms create risk of excessive sedation and respiratory depression

Long-term follow-up of patients with culture-confirmed Lyme disease
