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However, through the action of GPXs and catalase, H 2 O 2 is efficiently converted into water, preventing its transformation into more deleterious ROSs [9]

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Additionally, copper-deficient rats exhibited higher nuclear SREBP-1 Levels, attributed to reduced hepatic cholesterol and elevated GSH, which stimulated FAS expression and inhibited sphingomyelinase, enhancing SREBP-1 proteolytic release[130]

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